Manuscript: “A transcriptional toolbox for exploring peripheral neuro-immune interactions”

Manuscript: “A transcriptional toolbox for exploring peripheral neuro-immune interactions”

Pain journal has recently accepted to publish a manuscript from King’s College London on the transcriptomic analysis on purified sensory neurons performed in WP2.

The results are published: https://www.biorxiv.org/content/10.1101/813980v2

A public database has been created to allow other biologists easy access: http://rna-seq-browser.herokuapp.com/

Link to preprint pdf

IMI Stakeholder Forum 2019, Brussels, June 12th, 2019

POSTER link: IMI Stakeholder Forum 2019 It has been demonstrated that sensory neurons possess electrical activity in response to capsaicin already after few hours in vitro; however, in the case of purified neurons, this activity is largely reduced after 1 day in vitro. This cannot be explained by a lack in the capsaicin receptor TRPV1, whose presence has been proved…

BonnBrain3 Meeting, March 25th-27th, 2019

POSTER link: BonnBrain 2019_Final_PR Abstract: HUMAN IPSC-DERIVED PNS MONO- & CO-CULTURE SYSTEMS FOR PAIN AND SENSORY NEURON RESEARCH AND DRUG DISCOVERY In a physiological state pain is one of the most important senses in terms of survival and well being, but is very problematic when it develops under disease conditions into a chronic state. Sensation of pain is initiated by…