This Tuesday, November 12th, we had the last meeting of the NGN-PET project. The meeting was hosted by IMI, and due to the COVID-19 pandemia it was done virtually. The coordinator of the project, Paola Tarroni, and the project leader, Xavier Codony, presented the key achievements of the project, the exploitation and sustainability plans and the impact NGN-PET has already…
Manuscript: “A transcriptional toolbox for exploring peripheral neuro-immune interactions”
Pain journal has recently published a manuscript from King’s College London on the transcriptomic analysis on purified sensory neurons performed in WP2.
The results are published in PAIN: https://journals.lww.com/pain/FullText/2020/09000/A_transcriptional_toolbox_for_exploring_peripheral.16.aspx
A public database has been created to allow other biologists easy access: http://rna-seq-browser.herokuapp.com/
Final NGN-PET meeting, April 22nd-23rd.
The last General Assembly was held through videoconference due the travelling restrictions forced by COVID-19. The meeting was organised by Grünenthal and the attendants joined the meeting from home the most or from the lab in some cases. Despite the situation, the meeting was a great succeess. The latest results were presented and we had the opportunity to discuss and…
Set-up neuron-glia co-cultures for functional studies on multiple electrode arrays platforms
Set-up neuron-glia co-cultures for functional studies on multiple electrode arrays platforms
New poster presented at the 11th International Meeting on Substrate-Integrated Microelectrode Arrays
Neuron-glia co-cultures, towards better treatment options for neuropathic pain
NGN-PET coordinator, Paola Tarroni, did an interview for CORDIS
Find the interview at: https://cordis.europa.eu/article/id/413334-neuron-glia-co-cultures-towards-better-treatment-options-for-neuropathic-pain
5th Annual Neuroscience R&D Technologies Conference
Silvia Cainarca, from AXXAM, presented NGN-PET results at the 5th Annual Neuroscience R&D Technologies Conference
London, October 3rd, 2019
Advancing drug discovery: creating new iPSC reporter lines through genome editing
Poster at SLAS Europe 2019
Christina Kuhn, from AXXAM, presented a poster at the ‘Innovative Technologies for Tomorrow’s Discoveries’ meeting of the Society for Laboratory Automation and Screening.
IMI Stakeholder Forum 2019, Brussels, June 12th, 2019
POSTER link: IMI Stakeholder Forum 2019 It has been demonstrated that sensory neurons possess electrical activity in response to capsaicin already after few hours in vitro; however, in the case of purified neurons, this activity is largely reduced after 1 day in vitro. This cannot be explained by a lack in the capsaicin receptor TRPV1, whose presence has been proved…
MEA meeting 2018, Reutlingen, July 4th – 6th
POSTER link: MEA meeting 2018 It has been demonstrated that sensory neurons possess electrical activity in response to different excitatory stimuli already after 1 day in vitro; however, in the case of purified neurons, this activity disappears after 2 days in vitro. This cannot be explained by a lack in the capsaicin receptor TRPV1, whose presence has been proved by…
BonnBrain3 Meeting, March 25th-27th, 2019
POSTER link: BonnBrain 2019_Final_PR Abstract: HUMAN IPSC-DERIVED PNS MONO- & CO-CULTURE SYSTEMS FOR PAIN AND SENSORY NEURON RESEARCH AND DRUG DISCOVERY In a physiological state pain is one of the most important senses in terms of survival and well being, but is very problematic when it develops under disease conditions into a chronic state. Sensation of pain is initiated by…